Girihlet works on profiling the T cell receptor repertoire accurately to develop an understanding of the immune system. An accurate view of the repertoire is a window into the immune system and the health of an individual. Diagnostic and therapeutic applications can be derived from this technology. Our novel method of profiling the TCR repertoire is the basis of our work on TCR repertoires.

Another area of interest in the genetics of mtDNA, the final frontier in human genetics. mtDNA is increasingly of interest for its diverse roles and their implications for human disorders. Our novel approach to sequencing mtDNA has afforded us insights into mtDNA genetics and an ability to study heteroplasmy in mtDNA with great precision.